Numerical Simulation of the Influence of the Blood Flow Pattern in Venous Vessels in the Thrombus Formation

A numerical investigation of Newtonian and non-Newtonian steady blood flow in a complete idealized threedimensional venous model have recently been shown to provide prognostically relevant for hemodynamic data. The geometry reconstruction is essencial for the assessment of clinically relevant hemodynamic parameters. The blood flow patterns influence the development of thrombus that remains a significant problem in current clinical practice.This study is presented in in order to simulate numerically the influence of the blood flow pattern in venous vessels in the thrombus formation. Are acquired images of veins in Visible Human Project ® to construct the geometry in in the software Solid Works ® . The effects for two different sets of physiological parameters of laminar and turbulent blood flow was obtained running a computational fluid dynamics (CFD).Laminar Newtonian and non-Newtonian steady flow was adopted and compared with a turbulence flow model. The results show that shear stress gradient in non-Newtonian turbulence model, presented lower than non-Newtonian laminar flow.The shear stress distribution asymmetry,low shear stress, oscillatory shear strain rate and a combination of low velocity may also indicate areas at risk for thrombosis due to endothelial reorganization and venous stasis. These hemodynamics factors may contribute to further development of thrombus formation in venous vessels.